International studies and indicators show that the global burden of drug addiction-related diseases as a result of premature death, physical and mental disabilities and the spread of deadly and infectious diseases has led to the loss of 18 million “healthy” years of life. There are 2.8 million addicts in Islamic Republic of IRAN so we can consider that a significant proportion of this damage and cost is concentrated in our country. This article explains the pattern of combating drugs and addiction as the most important social harm in the country and conducts documentary studies and uses statistical findings during the fifth and sixth development plans (2011-2019) and performs comparative study of the different development indicators. This paper seeks a comprehensive, coherent and balanced paradigm in drug demand reduction and drug supply reduction with a social approach. The study shows that despite the growing trend of measures and quantitative and qualitative improvements in counter-narcotics performance during the three years of the Sixth Development Plan, compared to the Fifth Development Plan, but 65% of social and operational capacities remain unused. By mobilizing governmental and non-governmental resources and facilities and concentrating and activating unused capacities, it is possible to respond to the demands of the government and the people in this field while accelerating the movement towards the desired situation.